(Z)-4-Hydroxytamoxifen
Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
概要
(Z)-4-Hydroxytamoxifen is a cell-permeable selective estrogen receptor modulator (SERM) that binds to estrogen receptors (ER) and estrogen-related receptors (ERR) with both estrogenic and anti-estrogenic effects (Poulin et al.).
CANCER RESEARCH
· Suppresses tumor growth in breast cancer cells (Freiss et al.; Osborne et al.).
CANCER RESEARCH
· Suppresses tumor growth in breast cancer cells (Freiss et al.; Osborne et al.).
Alternative Names
trans-4-Hydroxytamoxifen; 4-OH-TAM; ICI 79280
Cell Type
Cancer Cells and Cell Lines
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Cancer Research
CAS Number
68047-06-3
Chemical Formula
C₂₆H₂₉NO₂
Molecular Weight
387.5 g/mol
Purity
≥ 98%
Pathway
Estrogen
Target
ER
技术资料
| Document Type | 产品名称 | Catalog # | Lot # | 语言 |
|---|---|---|---|---|
| Product Information Sheet | (Z)-4-Hydroxytamoxifen | 74052, 74054, 74056 | All | English |
| Safety Data Sheet | (Z)-4-Hydroxytamoxifen | 74052, 74054, 74056 | All | English |
数据及文献